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The Discovery Of The Pleasant-Tasting Aqueous Liquid Composition Of A Bitter-Tasting Drug

Pharma News Online

  A lot of people have always had difficulty choosing between drugs and injections. For so many, both are dreaded and without preference. The trick to get little children to take drugs have often been the introduction of a sweetener or something more appealing to their taste buds.
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This trick is not only recommended for children but also something that will be of great benefit to adults alike and in light of that, a Nigerian pharmacist came up with that groundbreaking and applaudable move of inventing and finding a way of making bitter-tasting drugs into liquid and pleasant-tasting drugs. This discovery has solved at least two earlier dreaded problems. One is that of the difficulty in swallowing solid drugs (tablets), while the second is that of the overly bitter taste of some drugs.

A Brief about Aloysius Anaebonam’s Background

Anaebonam Aloysius Onyeabo was born on 25 June 1955, to the family of George Nwoye Anaebonam and Maria Nneka (Ofoedu) Anaebonam, in Udi, Enugu State, Nigeria. His father, George, commonly referred to as “Akunne” or “Otutu Abagana”, was a well-treasured member of his community. He served as the private secretary to the military governor of Eastern Nigeria, Lt. Col. Ojukwu, from February 1966, till the end of the civil war. He also served as the secretary to several local governments in eastern Nigeria at different times before retiring as the deputy permanent secretary of the Ministry of Works, Enugu State, in 1984. Dr Anaebonam was an exceptional student with a great flair for the sciences. He gained admission in 1973 to study Pharmacy at the University of Nigeria, Nsukka and obtained his Bachelor of Pharmacy degree with first-class honours in 1978. He then relocated to the United States in 1980 for further studies and soon obtained his master’s and Doctor of Philosophy degrees in Industrial Pharmacy from the Massachusetts College of Pharmacy, Boston Massachusetts, in 1983 and 1986 respectively. But more than being just a nominal pharmacist, Aloysius Anaebonam is the Founder and Chief Scientist of BREEJ Technologies, Inc., a developer and marketer of advanced treatment cosmetics products for problem skin.
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He is credited with coming up with an aqueous liquid composition that comprises a pharmaceutically effective amount of a bitter-tasting drug that is dissolved or dispersed in an aqueous medium that is free of ethanol. This aqueous liquid has a pleasant taste when orally administered, although it has the same effect as the bitter-tasting drug.

Aloysius and the List of Some Patents

In addition to this discovery and innovation, Aloysius Anaebonam has other researches that have been patented in the United States of America. He holds about 12 U.S. Patents including the following: – Extended-release acetaminophen, Patent number: 6254891, July 3, 2001; – Extended-release acetaminophen particles, Patent number: 6126967, October 3, 2000; – Pleasant-tasting aqueous liquid composition of a bitter-tasting drug, Patent number: 5962461, October 5, 1999; – Pleasant-tasting aqueous liquid composition of a bitter-tasting drug, Patent number: 5763449, June        9, 1998; – Composition and process for prevention and treatment of cutaneous immediate hypersensitivity reactions, Patent number: 5684037, November 4, 1997; – Composition and process for prevention and treatment of cutaneous immediate hypersensitivity reactions, Patent number: 5684038, November 4, 1997; – Terfenadine oral granules, Patent number: 5626879, May 6, 1997; – Process for treating uremic pruritus, Patent number: 5576346, November 19, 1996; – Process for treating hemangioma, Patent number: 5552436 – Composition and process for prevention and treatment of cutaneous immediate hypersensitivity reactions, Patent number: 5532270, July 2, 1996; and – Terfenadine oral powder, Patent number: 5455049, October 3, 1995.

Major Discourse on Shaving Bumps

Anaebonam was the first scientist to disagree with the widely held view that shaving bumps are caused by “in-grown” hairs – wiry, curly hairs that curl and grow back into the skin. Ingrown hairs or, more appropriately, entrapped hairs, result when existing shaving bumps block the opening of the hair follicles on the skin, forcing the normally growing hairs to grow into the existing bumps. Anaebonam postulated that
“shaving bumps are primarily caused by the trauma from shaving, resulting in inflammation of the shaved area manifested as ‘bumps’ as the body reacts to the trauma, compounded at times by bacterial/fungal infections. Induction of melanogenesis by irritated keratinocytes during shaving produces additional inflammatory mediators exacerbating the condition. This is the main reason why black people with higher levels of melanin, have a higher incidence of shaving bumps.”
Sources: Pharma News Online All Nigeria Info NG Featured Image Source: Pharma News Online
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